Today the FDAissued a warning for the drugs valproate sodium, valproic acid and divalproex sodium(sold under the brand names Depakote, Depakote ER, Depakene and Depacon). They state that pregnant women should only use valproate if it is essential to manage their medical condition.They state that valproate has an increased risk of causing neural tube defects and other major birth defects such as craniofacial defects and cardiovascular malformations in babies exposed to it during pregnancy. They also state that the risks are particularly high if the drug is taken during the first trimester.
AsDepakote is a drug often used to treat bipolar disorder, I wanted to make sure my readers are aware of this. As always, discuss this with your doctor if you have concerns.